A few days ago it was revealed that diet soda can trigger strokes in regular drinkers of the sweet fizzy beverages. Now the Center for Science in the Public Interest is petitioning the U.S. Food and Drug Administration to prohibit what it says is carcinogenic “caramel coloring” (that is, not real caramel but synthetic, chemical “caramel”):
The “caramel coloring” used in Coca-Cola, Pepsi, and other foods is contaminated with two cancer-causing chemicals and should be banned, according to a regulatory petition filed today by the Center for Science in the Public Interest.
In contrast to the caramel one might make at home by melting sugar in a saucepan, the artificial brown coloring in colas and some other products is made by reacting sugars with ammonia and sulfites under high pressure and temperatures. Chemical reactions result in the formation of 2-methylimidazole and 4 methylimidazole, which in government-conducted studies caused lung, liver, or thyroid cancer or leukemia in laboratory mice or rats.
The National Toxicology Program, the division of the National Institute of Environmental Health Sciences that conducted the animal studies, said that there is “clear evidence” that both 2-MI and 4-MI are animal carcinogens. Chemicals that cause cancer in animals are considered to pose cancer threats to humans. Researchers at the University of California, Davis, found significant levels of 4-MI in five brands of cola.
“Carcinogenic colorings have no place in the food supply, especially considering that their only function is a cosmetic one,” said CSPI executive director Michael F. Jacobson. “The FDA should act quickly to revoke its approval of caramel colorings made with ammonia.”
Federal regulations distinguish among four types of caramel coloring, two of which are produced with ammonia and two without it. CSPI wants the Food and Drug Administration to prohibit the two made with ammonia. The type used in colas and other dark soft drinks is known as Caramel IV, or ammonia sulfite process caramel. Caramel III, which is produced with ammonia but not sulfites, is sometimes used in beer, soy sauce, and other foods.
Five prominent experts on animal carcinogenesis, including several who have worked at the National Toxicology Program, joined CSPI in calling on the FDA to bar the use of caramel colorings made with an ammonia process. “The American public should not be exposed to any cancer risk whatsoever as a result of consuming such chemicals, especially when they serve a non-essential, cosmetic purpose,” the scientists wrote in a letter to FDA Commissioner Margaret Hamburg.
CSPI also says the phrase “caramel coloring” is misleading when used to describe colorings made with ammonia or sulfite. The terms “ammonia process caramel” or “ammonia sulfite process caramel” would be more accurate, and companies should not be allowed to label any products that contain such colorings as “natural,” according to the group.
“Most people would interpret ‘caramel coloring’ to mean ‘colored with caramel,’ but this particular ingredient has little in common with ordinary caramel or caramel candy,” Jacobson said. “It’s a concentrated dark brown mixture of chemicals that simply does not occur in nature. Regular caramel isn’t healthful, but at least it is not tainted with carcinogens.”
In a little-noticed regulatory proceeding in California, state health officials have added 4 MI to the state’s list of “chemicals known to the state to cause cancer.”…
[continues at the Center for Science in the Public Interest]