Ketamine Is “The Most Important Discovery In 50 Years” For Treating Depression

So says a new review in the journal Science, which declares that the club drug is vastly more effective than the serotonin-boosting antidepressants typically prescribed for mood disorders. Via TIME Healthland:

It didn’t seem likely that a drug could repair brain cells within hours, but new research explored suggests just that. Ketamine rapidly spurs the growth of new synapses, the connections between brain cells, and is associated with “reversal of the atrophy caused by chronic stress,” the authors write.

Unfortunately, the hallucinogenic effects of ketamine mean that it can’t be used in the same way typical antidepressants are, and fears about its potential for misuse also hamper its development. Researchers are frantically trying to develop compounds that have the same effects as ketamine without producing a “high.”

In the meanwhile, however, ketamine is already FDA approved [...] But clinical use of the drug in the community remains rare. Fears about abuse continue to run high, though ketamine has never caught on as a major street drug. If the Science paper’s authors are right that ketamine’s effect on depression is a key advance — and if the drug really holds similar promise for bipolar disorder — patients might want to consider pushing for greater access. Ketamine is off patent, so no drug maker is likely to do so.

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  • http://buzzcoastin.posterous.com BuzzCoastin

    when establishment publications like Time & Science
    start trumpeting the benefits of Ketamine
    it’s time to seriously consider the source & their motives
    which historically, have never been pure

  • http://buzzcoastin.posterous.com BuzzCoastin

    when establishment publications like Time & Science
    start trumpeting the benefits of Ketamine
    it’s time to seriously consider the source & their motives
    which historically, have never been pure

    • David Howe

       always assume the most extreme paranoid scenario.  it will serve you well

    • David Howe

       always assume the most extreme paranoid scenario.  it will serve you well

      • http://buzzcoastin.posterous.com BuzzCoastin

         it would be extremely paranoid
        only if there wasn’t overwhelming evidence
        that Big Pharma is not to be trusted, nor their shills

      • http://buzzcoastin.posterous.com BuzzCoastin

         it would be extremely paranoid
        only if there wasn’t overwhelming evidence
        that Big Pharma is not to be trusted, nor their shills

  • Jon

    the last thing we need is bipolar ppl running around on K.. thats messy…

  • Jon

    the last thing we need is bipolar ppl running around on K.. thats messy…

  • KayWhole

    Mixing K with E can be fun, but K by itself can be absolutely brutal. K-holes are the absolute worst… 

  • KayWhole

    Mixing K with E can be fun, but K by itself can be absolutely brutal. K-holes are the absolute worst… 

  • Oonstoonst

    There may be truth in this. I just got back from Ibiza and practically everyone there was taking K. They all seemed pretty upbeat…

  • Oonstoonst

    There may be truth in this. I just got back from Ibiza and practically everyone there was taking K. They all seemed pretty upbeat…

  • KC

    I knew a really hot chick who told me she could read her friend’s mind when she took it.

    She asked me if I wanted to try it with her and I declined.

    Because I’m a dingus.

  • KC

    I knew a really hot chick who told me she could read her friend’s mind when she took it.

    She asked me if I wanted to try it with her and I declined.

    Because I’m a dingus.