BREAKTHROUGH: DMT Found in the Pineal Gland of Live Rats

siamese_seahorse_fractalIn a major breakthrough in consciousness and psychedelic studies, Cottonwood Research Foundation has published a paper (soon to appear in the Journal Biomedical Chromatography)  documenting the presence of DMT in the brains of living rats.

For decades researchers have hypothesized that DMT may be one of the neurochemicals responsible for consciousness, dreams and visionary experiences. It’s certainly responsible for these and ever weirder experiences for those who have smoked it or taken Ayahuasca. DMT has been documented as naturally occurring in human blood, but this was not conclusive evidence that it is produced in the brain. DMT is structurally related to Serotonin, Melatonin and Pinoline, so the small traces in human blood could be an enzymatic breakdown product of these precursor molecules.

Now we have clear proof of DMT being manufactured in the living Pineal Glands of rats, and that the genes responsible for this exist in the Pineal Gland and Retina! The first implication is that Yes, it truly is a natural neurochemical responsible for modulating consciousness.  It is not a foreign substance to the body & mind of mammals. Also, if found in rats in this context then it is almost certain to function similarly in humans.

From the press release:

We’re excited to announce the acceptance for publication of a paper documenting the presence of DMT in the pineal glands of live rodents. The paper will appear in the journal Biomedical Chromatography and describes experiments that took place in Dr. Jimo Borjigin’s laboratory at the University of Michigan, where samples were collected. These samples were analyzed in Dr. Steven Barker’s laboratory at Louisiana State University, using methods that funding from the Cottonwood Research Foundation helped develop.

The pineal gland has been an object of great interest regarding consciousness for thousands of years, and a pineal source of DMT would help support a role for this enigmatic gland in unusual states of consciousness. Research at the University of Wisconsin has recently demonstrated the presence of the DMT-synthesizing enzyme as well as activity of the gene responsible for the enzyme in pineal (and retina). Our new data now establish that the enzyme actively produces DMT in the pineal.

The next step is to determine the presence of DMT in cerebrospinal fluid (CSF), the fluid that bathes the brain and pineal. CSF is a possible route for pineal-synthesized DMT to effect changes in brain function. Successfully establishing DMT’s presence in this gland adds another link in the chain between the pineal and consciousness and opens new avenues for research.

More info at Cottonwood Research Foundation

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  • echar

    Awesome!

    • Monkey See Monkey Do

      It was a good call by Dr. Strassman.

  • Matt Staggs
    • echar

      That’s crap lousy!

      • Matt Staggs

        PUNY MAN ANIMAL!

        • echar

          There are strong parallels to Battlefield Earth (1982). and La Planete Sauvage (1973). Hubbard would never do such a thing! Considering he was a nuclear physicist, blood brother to native Americans, and other impressive things.

          P.S. I don’t understand why Battlefield Earth tanked. Much like Water World. Poor science Fiction, always getting the short end of the stick.

          • Matt Staggs

            “Poor science fiction”, indeed.

          • Mark Wheeler

            I love Fantastic Planet but Hubbard… not so much.

          • echar

            I like The Battlefield Earth movie, but I am right there with ya on Hubbard. I was poking fun at him. There’s all sorts of fantastic claims made by him and about him.

          • Noah_Nine

            he was a genius of gibberish…. when I listen to some of the recordings of him explaining some of the higher levels of scientology I can tell he’s making that shit up on the spot… I would have loved to hear him audit someone like Charles Manson… 2 high powered bullshit masters going at it… it would be a beautiful thing to behold…

  • geminihigh

    Finally, its conclusive. Now, if you want to be truly drug-free, go cut out your pineal gland. extract of pineal… yum!

  • stufferson

    Truly a gift from Eris.

  • s1nn3r

    can someone link the paper/ tell us when the paper will be posted?

  • BuzzCoastin

    most animals can live in the wild and
    in circumstances that are much more harsh
    than humans usually have to face
    and yet
    wee assume they have no consciousness & can’t think?
    wee assume they are automatons living a program called wildlife
    they must think humans are idiots

    • http://www.psychedelicfrontier.com/ Psychedelic Frontier

      Well put! Reminds me of what philosopher Jeremy Bentham said about our moral responsibility toward animals, fighting the then (and still) popular view of animals as biological clockworks:

      “The question is not, Can they reason? nor, Can they talk? but, Can they suffer?”

  • Noah_Nine

    I wish DMT were easier to get my hands on around here…. I’ve only had the opportunity to try it a few times in one session and would do it again without hesitation… LSD I avoid these days because it’s at least a 48 hour commitment… Mushrooms always mess up my stomach and cause me to have an uncomfortable trip… Ketamine was fun for awhile but was always a darker experience, ultimately not trustworthy… but DMT was absolutely stunning… I wish I could get my hands on some… I have some psychic work to do and it would really help…