Child Abuse Changes Gene Activity Patterns

TonitzaOrfanderazboiIt looks like child abuse does more than leave physical and emotional scarring: It changes its victims on a genetic level.

Via Medical News Today:

A study of adult civilians with PTSD (post-traumatic stress disorder) has shown that individuals with a history of childhood abuse have distinct, profound changes in gene activity patterns, compared to adults with PTSD but without a history of child abuse.

A team of researchers from Atlanta and Munich probed blood samples from 169 participants in the Grady Trauma Project, a study of more than 5000 Atlanta residents with high levels of exposure to violence, physical and sexual abuse and with high risk for civilian PTSD.

The results were published recently in Proceedings of the National Academy of Sciences, Early Edition.

“These are some of the most robust findings to date showing that different biological pathways may describe different subtypes of a psychiatric disorder, which appear similar at the level of symptoms but may be very different at the level of underlying biology,” says Kerry Ressler, MD, PhD, professor of psychiatry and behavioral sciences at Emory University School of Medicine and Yerkes National Primate Research Center.

Keep reading.

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  • Andrew

    Looks like the APA is going to have to rethink their refusal to include C-PTSD in the DSM5.

    • Matt Staggs

      Have you been keeping up with the DSM5 controversy? I think NIMH rejected it. In my opinion, it’s really more useful for insurance coding than anything else – provided that you’re lucky enough to have decent mental health care coverage in your insurance plan.

  • DeepCough

    I’ll admit, this is interesting, but more study is needed in the area of gene expression.

    • emperorreagan

      Points strongly to a need to actually study things rather than rushing to the market with genetic testing or manipulating genetics…

  • mannyfurious

    So the mind and body ARE connected. Interesting….

    • http://hormeticminds.blogspot.com/ Chaorder Gradient

      Heresy!

    • Jin The Ninja

      TCM has been saying that for 5000 years.

  • BuzzCoastin

    given the rapid exponential nature of the roll out of disruptive technologies
    during the last 100 years, especially the last 50
    coupled with the complete destruction of the old ways of being
    anyone living within cell phone range has PTSD

    • echar

      Anyone conscious of world events, which largely excludes kids, the mentally retarded, and vegetables.

      • BuzzCoastin

        the average middle class 4 year old
        has access to an iPhone and iPad
        the average 4 year old has access to 500 channel cable &
        hosts of other electronic gizmoz
        and vegetables have not been excluded from the assault
        as GMO Corn McNuggets* can attest

        *with real chicken flavo flave

        • echar

          Do you think they understand the context though?

          • BuzzCoastin

            I don’t think the adults even understand the context
            the context is not the content
            the context the invisible electric environment
            created by the electronic devices

            these electric environments are less than 100 years old
            some are only decades old
            it’s hard to be aware of that

          • echar

            Oh you mean radio waves?

          • BuzzCoastin

            no
            I mean electric environments
            electric environments use electricity
            they way plants use dirt

            ever see someone you’re talking to
            constantly glance at their dumb phone?
            that’s an electric environment they’re in
            and it seems odd to anyone not sharing that environment
            but it does not seem odd to the other disembodied persons
            sharing that environment

          • echar

            Yes, an acquaintance of mine would get a call during a meal and then talk on the phone. It’s very rude.

          • BuzzCoastin

            you’re not getting the electric environment thing
            not surprising
            but it’s basic media ecology since about 1965

            McLuhan:
            * Environments are invisible. Their groundrules, pervasive structure, and overall patterns elude easy perception.

            * Media, by altering the environment, evoke in us unique ratios of sense perception…When these ratios change, men change.

            * Electric circuitry profoundly involves men with one another. Information pours upon us, instantaneously and continuously.

            * My work is designed for the pragmatic purpose of trying to understand our technological environment and its psychic and social consequences.

          • echar

            Do you mean it’s messes with us like how it is thought to mess with bees and birds?

          • BuzzCoastin

            the fact the you don’t even think there are electric environments
            & that you judge that the OCD that comes with a dumb phone
            as rudeness and not an electric effect of that environment
            is evidence that it has already messed with you

            so it not only messes with us the way it does with animals
            it does so at even more subtle & profound levels
            so that wee don’t even suspect it as having any effect at all
            and so the zombies do the machine’s bidding unaware

          • echar

            This sounds like an excellent topic to share with everyone.

          • BuzzCoastin

            we just did
            however, Marshall McLuhan & a guy who calls himself Bob Dobbs
            (aka: Bob Dean, Bob Nevritt)
            have covered this stuff thoroughly
            and Bob & I have done about 1000 videos about this subject
            many of which can be found at these locations:
            http://www.youtube.com/user/BobDobbsTown2
            http://vimeo.com/bobdobbstown
            http://www.youtube.com/user/BobDobbsTown22
            http://www.youtube.com/user/MyCluein22

          • echar

            woah man!

            My immediate response

            http://www.youtube.com/watch?v=Kb8zCsjcNvk

            Now that I got that out of my system. Do you mean the electric environments are augmenting us in a negative way? A dude I met in AK hated cell phones, he said they are screwing up our memory. Much like the affect digital clocks and calculators can have.

            Thanks for the links :)

          • BuzzCoastin

            all technologies and natural systems create invisible environments
            (water is invisible to fish, air is mostly invisible to us)
            water creates an environment
            air creates an environment
            the telephone creates an environment
            the internet creates an environment
            the iPad creates an environment
            etc etc etc

            all these environments have effects
            these effects bring services & disservices
            and too much is as bad as too little

            our human memories
            have been more greatly impacted by the alphabet & printing
            they by the rather late cellphone
            one of the disservices of the cellphones
            is that it makes hiding almost impossible
            and my personal favorite disservice
            the automobile created the police state

          • echar

            The cameras on the cell phones can capture those who do not own them. How’s that for a thought. I found this, I wished there was more. I think the site has fallen to disrepair.

            http://www.fivebody.com/Home_Page.php

            It was referenced in an interview with Harold Channer.

          • BuzzCoastin

            the archive is here, you’re right the site is fucked
            http://www.fivebodied.com/archives/audio/catalog/CompleteBobTimeline.html
            yeah he did several things with Harold

            I haven’t worked with Bob in few years now
            he’s off to different things
            and it looks like the fivebodied site is no longer a priority

          • echar

            Wonderfully weird stuff!

          • echar

            So the medium is the message means that content is a distraction?

          • BuzzCoastin

            because our bias is towards content
            Mac always emphasized that
            the medium had a significantly greater effect than content
            so that content hides the real effect of media
            digital OCD, the police state, civilization as farce
            are all effects of media

            MS Excel runs all business
            no one ever checks the formulas
            they just assume it’s right
            and do what it tells them to do
            without thinking
            it was MS Excel that moved the jobs in America overseas
            it’s human servants simply did it’s bidding

          • echar

            Audio visual opiates? What if the mind can augment to use the medium as a nootropic?

          • BuzzCoastin

            electric media is way more psychedelic than psychedelics
            but not as enlightening
            I haven’t had good experiences mixing the two
            except maybe scroomm honey tea at a rave
            but once I got sucked into a Lord of the Rings CD
            while smoking salvia

          • echar

            When I smoked Salvia I saw rainbows roll off the arms of an Athabascan woman, and all my senses were heightened for a week after that.

            I sometimes wonder about audio and visual snippets hidden within internet videos. I also wonder about layered binaural beats. They could/may be used.

          • BuzzCoastin

            the CIA has long used electric media at subtle levels
            this is one of the reasons they stopped doing LSD research
            electric technology was more effective in every way

          • echar

            The affects of LSD are unpredictable.

          • BuzzCoastin

            not only that
            but the effects of electric technology are predictable
            though they do tend to focus on content
            but it usually works anyway
            because they are puppets of the technology too
            and are as clueless as their victims about what they’re doing
            and what is making them do what they do

          • echar

            A ghost in the machine?

          • BuzzCoastin

            I don’t think the technology is conscious with an agenda
            (some do)
            but I do think its effects are its effects regardless
            this is true of all technologies

            language is a software technology
            each language shapes the way you think
            without your ever being aware of that fact
            as do all the other technologies

            McLuhan was taking a inventory of effects
            trying to understand what technology had done & is doing to us

          • echar

            I see, something like what Rosalind Franklin created for herself?

          • echar

            Perhaps we can continue this tomorrow. It’s getting late. Goodspeed you Buzz

          • BuzzCoastin

            this is one of the first vidz I did with Bob
            it mixes Harold talking with Bob & McLuhan interjecting
            http://vimeo.com/19699390

            http://vimeo.com/19699390

          • echar

            Dude… I was literally watching that exact thing. The odd thing is that I rewound to that spot. You’re freakin’ me out maaaannn! lol

            anyhow… digital cut ups?

          • BuzzCoastin

            I started out massing up McLuhan stuff
            Bob saw it & contacted me &
            we ended up with a lot of stuff in 2 years
            that cutup was pretty tame
            by the end of year 2
            they were totally trippy

          • echar

            I saw some of the totally trippy stuff. I have it saved and I will look through it. I see you are using the female form to distract recently.

          • BuzzCoastin

            > I see you are using the female form to distract recently.

            it’s the most widely used meme in advertizing
            tits sell

          • echar

            There’s a reason why the magician’s assistant is female and typical well endowed.

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