FDA approves first GMO Flu Vaccine containing Reprogrammed Insect Virus

via Jonathan Benson Global Research tumblr_ljpaexBSmS1qegchao1_500

A new vaccine for influenza has hit the market, and it is the first ever to contain genetically-modified (GM) proteins derived from insect cells. According to reports, the U.S. Food and Drug Administration (FDA) recently approved the vaccine, known as Flublok, which contains recombinant DNA technology and an insect virus known as baculovirus that is purported to help facilitate the more rapid production of vaccines.

According to Flublok’s package insert, the vaccine is trivalent, which means it contains GM proteins from three different flu strains. The vaccine’s manufacturer, Protein Sciences Corporation (PSC), explains that Flublok is produced by extracting cells from the fall armyworm, a type of caterpillar, and genetically altering them to produce large amounts of hemagglutinin, a flu virus protein that enables the flu virus itself to enter the body quickly.

So rather than have to produce vaccines the “traditional” way using egg cultures, vaccine manufacturers will now have the ability to rapidly produce large batches of flu virus protein using GMOs, which is sure to increase profits for the vaccine industry. But it is also sure to lead to all sorts of serious side effects, including the deadly nerve disease Guillain-Barre Syndrome (GSB), which is listed on the shot as a potential side effect.

“If Guillain-Barre Syndrome (GBS) has occurred within six weeks of receipt of a prior influenza vaccine, the decision to give Flublock should be based on careful consideration of the potential benefits and risks,” explains a section of the vaccine’s literature entitled “Warnings and Precautions.” Other potential side effects include allergic reactions, respiratory infections, headaches, fatigue, altered immunocompetence, rhinorrhea, and myalgia.

According to clinical data provided by PSC in Flublok’s package insert, two study participants actually died during trials of the vaccine. But the company still insists Flublok is safe and effective, and that it is about 45 percent effective against all strains of influenza in circulation, rather than just one or two strains.

FDA also approves flu vaccine containing dog kidney cells

Back in November, the FDA also approved a new flu vaccine known as Flucelvax that is actually made using dog kidney cells. A product of pharmaceutical giant Novartis, Flucelvax also does away with the egg cultures, and can similarly be produced much more rapidly than traditional flu vaccines, which means vaccine companies can have it ready and waiting should the federal government declare a pandemic.

Like Flublok, Flucelvax was made possible because of a $1 billion, taxpayer-funded grant given by the U.S. Department of Health and Human Services (HHS) to the vaccine industry back in 2006 to develop new manufacturing methods for vaccines. The ultimate goal is to be able to quickly manufacture hundreds of millions of vaccines for rapid distribution.

Meanwhile, there are reportedly two other GMO flu vaccines currently under development. One of them, which is being produced by Novavax, will utilize “bits of genetic material grown in caterpillar cells called ‘virus-like particles’ that mimic a flu virus,” according to Reuters.

 

 

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  • Heath

    Two people die during the study, its safe, no really!

    • Simon Valentine

      it’s possible they are required to test on people who have a higher chance of dying (yes i know “according to what?”) as well as … well. that’s about it. i’d prefer to read (forthcoming and intelligible) specifics about how it was done.

    • http://wildernessvagabonds.com/ Mike Lewinski

      Quoting from the FDA report:

      “Both deaths occurred more than 28 days following vaccination and neither was considered vaccine-related.”

      There were 4,648 subjects in the randomized clinical trial. Of them, 2,344 received Flublok and 2,304 received a placebo. One participant from each group died during the 6 month followup monitoring period (meaning one of those deaths was in a person who didn’t receive the Flubok vaccine at all).

      http://www.rxlist.com/flublok-side-effects-drug-center.htm

      You can expect in a group of almost 5,000 people that there may be wholly random deaths and other serious illnesses during a six month period that have nothing to do with the trial at all. If the person who received the vaccine was hit and killed by a car, that is still reported as a death because it is relevant to the study (no disrespect to the person’s life intended, it’s also a loss of a data point and good science demands that it be recorded).

  • kowalityjesus

    Is genetic engineering here to stay? The uncomfortable truth is yes.

    • BuzzCoastin

      it’s not here to stay
      it’s here to do away with humans
      once the humans are gone
      it gone too
      GM needs humans, not the other way around

  • Haystack

    Well, if it involves using cells from insects, dogs, or other animals that we think of as unclean, then clearly it must be medically unsound. Also, picking up a toad can give you warts.

    The traditional influenza-based vaccine contains the same warning against GSB. GSB is an autoimmune disorder, so vaccines (which operate by triggering the immune system) can trigger GSB. This happens about one time in a million, and most people who get GSB fully recover after a short time. The influenza virus, by contrast, can be quite deadly, particularly among vulnerable populations (e.g., the elderly), or in its more virulent strains.

    This article is filled with scare words, designed to stoke fear of vaccines on behalf of those who are ideologically opposed to scientific medicine. No attempt is made to consider the potential benefits of such a vaccine. It is telling, for example, that the author points out the “increased profits for the vaccine industry” of greater production, while neglecting to consider the lives that can be saved by having more shots available–especially given that we live under a very real risk of a major flu pandemic within our lifetimes.

  • BuzzCoastin

    pick yer poison:
    if your immune system is shit
    get a vaccine & possibly die
    or
    don’t get a vaccine
    and get the flu and possibly die

    I think the key is doing everything possible to keep the immune system healthy
    until you die

    • http://wildernessvagabonds.com/ Mike Lewinski

      Except sometimes it’s your healthy immune system that actually kills you. For example, during the 1918 flu epidemic mostly young healthy people died, apparently due to cytokine storm caused by their own immune response.

      See the excellent (if somewhat dated) book “Lives of a Cell” by Lewis Thomas.

      http://weiyu51na.com/documents/cell_en.pdf

      The microorganisms that seem to have it in for us in the worst way–the ones that really appear to wish us ill–turn out on close examination to be rather more like bystanders, strays, strangers in from the cold. They will invade and replicate if given the chance, and some of them will get into our deepest tissues and set forth in the blood, but it is our response to their presence that makes the disease. Our arsenals for fighting off bacteria are so powerful, and involve so many different defense mechanisms, that we are in more danger from them than from the invaders. We live in the midst of explosive devices; we are mined.

      It is the information carried by the bacteria that we cannot abide.

      The gram-negative bacteria are the best examples of this. They display lipopolysaccharide endotoxin in their walls, and these macromolecules are read by our tissues as the very worst of bad news. When we sense lipopolysaccharide, we are likely to turn on every defense at our disposal; we will bomb, defoliate, blockade, seal off, and destroy all the tissues in the area. Leukocytes become more actively phagocytic, release lysosomal enzymes, turn sticky, and aggregate together in dense masses, occluding capillaries and shutting off the bleed supply. Complement is switched on at the right point in its sequence to release chemotactic signals, calling in leukocytes from everywhere. Vessels become hyperreactive to epinephrine so that physiologic concentrations suddenly possess necrotizing properties. Pyrogen is released from leukocytes, adding fever to hemorrhage, necrosis, and shock. It is a shambles.

      All of this seems unnecessary, panic-driven. There is nothing intrinsically poisonous about endotoxin, but it must look awful, or feel awful, when sensed by cells. Cells believe that it signifies the presence of gram-negative bacteria, and they will stop at nothing to avoid this threat.

      I used to think that only the most highly developed, civilized animals could be fooled in this way, but it is not so. The horseshoe crab is a primitive fossil of a beast, ancient and uncitified, but he is just as vulnerable to disorganization by endotoxin as a rabbit or a man. Bang has shown that an injection of a very small dose into the body cavity will cause the aggregation of hemocytes in ponderous, immovable masses that block the vascular channels, and a gelatinous clot brings the circulation to a standstill. It is now known that a limulus clotting system, perhaps ancestral to ours, is centrally involved in the reaction. Extracts of the hemocytes can be made to jell by adding extremely small amounts of endotoxin. The self- disintegration of the whole animal that follows a systemic injection can be interpreted as a well-intentioned but lethal error. The mechanism is itself quite a good one, when used with precision and restraint, admirably designed for coping with intrusion by a single bacterium: the hemocyte would be attracted to the site, extrude the coagulable protein, the microorganism would be entrapped and immobilized, and the thing would be finished. It is when confronted by the overwhelming signal of free molecules of endotoxin, evoking memories of vibrios in great numbers, that the limulus flies into panic, launches all his defenses at once, and destroys himself.

      It is, basically, a response to propaganda, something like the panic-producing pheromones that slave-taking ants release to disorganize the colonies of their prey. I think it likely that many of our diseases work in this way. Sometimes, the mechanisms used for overkill are immunologic, but often, as in the limulus model, they are more primitive kinds of memory. We tear ourselves to pieces because of symbols, and we are more vulnerable to this than to any host of predators. We are, in effect, at the mercy of our own Pentagons, most of the time.

      • BuzzCoastin

        over our recorded history
        Nature has from time to time cleaned house
        until about 200 years ago
        large numbers of humans died during plagues
        even with healthy immune systems

        modern medicine has forestalled these plagues
        whether or not they’ve been banished remains to be seen