Ibuprofen Leads to Leaky Gut

Equate Ibuprofen Pills and BottleSo many people take ibuprofen or brand name versions of it like Motrin that it’s almost become the 21st century aspirin, doled out to any family member feeling sick, worried about getting sick, or about to undergo strenuous exercise. But before you reach into the medicine cabinet, consider this report from the Daily Beast:

…Recently, some gluten-free champions have revisited studies from the past 20 years that show NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen might just play a contributing role by increasing the likelihood of leaky gut syndrome. According to one NIH study, “All the conventional NSAIDs studied were equally associated with small intestinal inflammation apart from aspirin…” and “intestinal permeability changes were significantly more pronounced” with some of the tests.

There is also evidence that NSAIDs cause intestinal damage when taken in conjunction with exercise. “This is the first study to reveal that ibuprofen aggravates exercise-induced small intestinal injury and induces gut barrier dysfunction in healthy individuals. We conclude that non-steroidal anti-inflammatory drugs consumption by athletes is not harmless and should be discouraged.”

And from as far back as the 1980s, a study found “NSAIDs are thus shown to disrupt intestinal integrity and long term treatment leads to inflammation of the small intestine.”…

[continues at the Daily Beast]


Majestic is gadfly emeritus.

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3 Comments on "Ibuprofen Leads to Leaky Gut"

  1. Gjallarbru | Apr 22, 2014 at 1:27 pm |

    A chemical, never found in nature, is screwing an organ made to digest food? You don’t say. I would never have thought that medication had side effects.

    • disqus_Ub4fvwt0g2 | Apr 22, 2014 at 6:50 pm |

      oh so if it is found in nature all is well. I’ll be sure to take a shot ob cobra venom before I go to bed tonight.

      • Gjallarbru | Apr 22, 2014 at 7:10 pm |

        You forgot the part about digesting food, or you just didn’t read it, or had to twist words to make a funny?

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