Author Archive | Yugen

Mystery School in Hyperspace: A Cultural History of DMT

dmtNew book on DMT, one of the weirdest psychedelic neurotransmitters this side of the milky way, by Graham St. John. The West has known about DMT since the 50s, yet we know extremely little about how it has impacted society since then. This is surprising, considering how earth-shattering the experience is. Perhaps its ability to elude linguistic description is partially to blame. Or perhaps there is more than meets the eye to its history and true impact.

Via The Nexian:

A great new book has been published that explores the rise of DMT in our culture. Knowing where we’ve been with this enigmatic molecule and how it has become entangled within our culture is vital to understanding where we are going as the second psychedelic rennaisance continues to unfold into the future. Herein you will also find art donated by DMT-Nexus members Cyb and Art Van D’lay.

Since the mid-1950s, the psychoactive compound DMT has attracted the attention of experimentalists and prohibitionists, scientists and artists, alchemists and hyperspace emissaries.… Read the rest

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DMT – A Tool to Extend Survival in Clinical Death?

Via Indiegogo

Imagine your loved one underwent a heart attack, suffered a stroke, lays in coma after an accident, or got electrocuted while changing a light bulb and the doctors are telling you they wish if they had more time to save their life. This project is for those who have gone through something similar, know well how it feels losing critical minutes, and for those who think ahead and want to be in a better position if something fatal happens to them or around them. Imagine, that the rescue comes from a scheduled drug: dimethyltryptamine (DMT)!

We are a group of basic and clinical researchers who follow the line of investigation started by Stephen Szara’s groundbreaking clinical studies with DMT. We are among the first ones who broke away of the mainstream scientific view of DMT as a psychopathological agent and proposed a somatophysiological role for this endogenous tryptamine, which is naturally occurring in the body.… Read the rest

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Vines and Minds — The DMT-Nexus at Aya2014

Via The Nexian:

This presentation was given by Raph Borges and David Nickles at the Aya2014 conference in Ibiza, Spain.

Despite numerous published scientific papers and anecdotal reports indicating the presence of DMT in a wide variety of plants, there is much ambiguity, contradiction, and speculation regarding the actual chemical composition of many of these plants. Discussions of indigenous preparations, which include DMT-containing plants, often treat the phytochemistry of the β-carboline-containing plants as fairly uniform. However, new examinations of these plants, utilizing modern analytical techniques, have shown them to contain a variety of compounds in differing ratios.

The DMT-Nexus has carried out unique chromatography and mass spectrometry analyses of specimens reported to contain DMT and β-carbolines, from both novel and previously examined species complexes. Thus far, we have tested species within the Acacia, Phalaris, Psychotria, Banisteriopsis and related genera, as well as Mimosa tenuiflora and Diplopterys cabrerana.

This research has elucidated questions and hypotheses regarding: indigenous botanical preparations; identities of plants found in the global market of entheogenic vendors; and the phytochemistry of plants that ethnobotanical researchers encounter in their own geographic regions.… Read the rest

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Harmine in the Treatment of Type 1 Diabetes


Via The Nexian: 

Harmine, one of the main chemical constituents of both ayahuasca vine (Banisteriopsis caapi) and Syrian rue (Peganum harmala), is making headlines this week for its potential use in treating type 1 diabetes.

Being a natural beta-carboline and monoamine oxidase inhibitor (MAOI), harmine is mostly known in the west for its ability to make DMT orally active, however, it has its own host of effects as well. In addition to itself being a unique psychedelic (…it was originally named telepathine), it also holds a wide variety of medicinal applications and has a long history of use in its plant forms.

The recent study is titled ‘A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication’. Researchers at the Icahn School of Medicine at Mount Sinai screened over 100,000 potential drugs, and only harmine drove human insulin-producing beta cells to multiply.… Read the rest

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Transcending Boundaries: Identity and Oppression Within Psychedelic Culture

Wise words from VTSeeker48, of the DMT-Nexus, highlighting how even the so called counter-culture still heavily suffers from the conditioning and pitfalls of existing within the framework of western society. Via The Nexian:

cyb metamorph

Cyb – Metamorph

“Psychedelics are illegal not because a loving government is concerned that you may jump out of a third story window. Psychedelics are illegal because they dissolve opinion structures and culturally laid down models of behaviour and information processing. They open you up to the possibility that everything you know is wrong.”

“Part of what psychedelics do is they decondition you from cultural values. This is what makes it such a political hot potato. Since all culture is a kind of con game, the most dangerous candy you can hand out is one which causes people to start questioning the rules of the game.”

–Terence Mckenna

The popularity of psychedelic experiences has skyrocketed in recent years with the advent of the internet and widespread acclaim of Ayahuasca and DMT.Read the rest

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Psilocybin: The Science behind a Magical Molecule

Excellent summary of some of the recent scientific research on the main constituent of psychedelic fungi via The Nexian:

Liberty CapsPsilocybin is a naturally occurring psychedelic compound found in many species of mushrooms. In this form it has a long history of use by humanity in the context of healing and divination, and it is still employed in this manner today by indigenous groups such as the Mazatec. Since the 1960’s awareness of psilocybin and the fungi within which it resides has spread into the Western world. Following the legal clamp down that resulted from widespread use of this and other psychedelics like LSD and mescaline at this time, scientific research into this compound and other psychedelics all but drew to a halt. In the last few years regulatory red tape has been loosening to some degree, and scientists have began studying psilocybin for a number of reasons. It appears that psilocybin is a highly multifaceted compound and has the capacity to act as a profound tool in the study of the brain and consciousness, as well as act as a treatment for a variety of psychological conditions.… Read the rest

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Turn On, Tune In, Rise Up: DMT, Globalization, and Radical Psychedelic Engagement

This presentation was given by David Nickles at Liminal Village at the 2014 Boom Festival in Idanha-a-Nova, Portugal. David is a moderator on the DMT-Nexus forum and contributing editor with The Nexian:

Forty-three years after the UN Convention on Psychotropic Substances imposed global prohibition on psychedelic compounds, demarcating governmental efforts to end the first psychedelic revolution, a second major psychedelic awakening is underway. Set amidst the landscape of late capitalism, this resurgence is unfolding in the forms of renewed focus on sanctioned psychedelic research, the emergence of significant underground psychedelic research, and the rhizomorphic spread of global festival cultures.

The role of DMT in this “archaic revival” is impossible to ignore. From Nick Sands’ discovery that DMT freebase could be smoked in the early 60’s, to Terence McKenna’s discussions of the vaporized DMT experience sowing seeds in countless imaginations during the 80’s and 90’s, to the rise of internet forums and the DMT-Nexus in the 21st century, distributing information rendering the molecule accessible worldwide, DMT has manifested itself into popular consciousness at a truly astonishing rate.… Read the rest

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The Ayahuasca Dialogues

If you’re concerned about the future of psychedelic medicines and ethical/sustainable sources, then please support this project by the Ethnobotanical Stewardship Council. They are making big strides and can use all our help.

From The Nexian:

With the continued rise in popularity of psychedelic plant medicines, concerns surrounding sustainable harvesting methods and safe administration by practitioners are growing. The Ethnobotanical Stewardship Council is a nonprofit organization dedicated to ensuring the sustainable and safe use of traditional plants and enriching the communities who work with them.

As we have seen in recent articles, unsustainable harvesting is a growing issue with ayahuasca, mimosa and acacia trees, iboga, peyote, and even sassafras in SE Asia. Quite antithetical to the earth-centered teachings of these plants, these harvesting methods have a devastating impact on the environment.

In order to truly heal with the planet we must not only have these experiences of higher awareness of the biosphere, but put our thoughts into action and become the stewards of nature, not its disease.… Read the rest

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Sustainable Psychedelics: Cultivating a Viable Relationship with the Medicine

Moderator dreamer042 of the DMT-Nexus elaborates on more sustainable approaches to utilizing psychedelics:

As the global demand for entheogenic medicines 1grows, we are seeing a simultaneous rise in unsustainable harvesting, poaching, and related ecological damage. The question we, as responsible explorers of expanded consciousness, should be asking is, “What are the hidden costs associated with my personal path of healing through medicine work?” From the cultural and environmental impact of the ever-growing ayahuasca tourism industry in the Amazon, to the ripping up of mature mimosa trees for their root bark in Brazil, to the stripping of protected acacia trees in Australia, to the poaching of iboga to near extinction in Africa, to the destruction of what remains of the ever shrinking North American peyote habitat. It’s time for a radical shift in the way we relate to these sacred plant teachers.

You will often hear people endlessly expounding on the idea that you should never drink ayahuasca without a shaman or that the only way to have an authentic experience is to jet-set halfway around the world and attend a ceremony in Peru or Gabon.… Read the rest

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When DMT Equals Killing the Environment

The dark side of DMT production…These atrocities have been going on for a very long time. If you read this link, you can see that the same thing has been and is happening with Mimosa hostilis, along with other psychedelic containing species, since at least the 90’s…

If you truly value the environment and profound teachings these plants offer humanity then please help us spread awareness of this idiotically unsustainable harvesting by sharing this information with others.

Via The Nexian:

In late September of this year (2014), Australian acacia expert, Nen, was confronted with one example of the potential ecological costs of the skyrocketing interest in DMT. The following is his account of what he encountered:

What I saw yesterday has left me sickened and shocked.

I took the Nexian, Spice Sailor, to see a very special and pristine nature reserve in a national park where there were large mother seed trees of Acacia obtusifolia.

Read the rest
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