Tag Archives | Disease

Tuberculosis Strain Totally Resistant To Antibiotics Spreads In India

Sputum sample containing Mycobacterium tuberculosis

Sputum sample containing Mycobacterium tuberculosis

Are we approaching the end of the wondrous age of antibiotics? Scientists have nothing to combat this strain of TB, as Eryn Brown  reports for the LA Times:

At least a dozen people in India are infected with a type of tuberculosis that is resistant to all antibiotics used to treat the disease.

In December, the journal Clinical Infectious Diseases published an online report that documented four of the cases. This weekend, news outlets in India reported that there were actually at least 12 people with the drug-resistant lung disease.

Officials fear that what they’ve seen so far is just the beginning, and that many more cases are lurking undetected.

“It’s estimated that on average, a tuberculosis patient infects 10 to 20 contacts in a year, and there’s no reason to suspect that this strain is any less transmissible,” study co-author Zarir Udwadia of the Hinduja National Hospital and Medical Research Centre in Mumbai told New Scientist.

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UN Forces Spread Deadly ‘Superbug’ Strain Of Cholera

UN peacekeeper in Haiti. Photo: Robert Miller (CC)

UN peacekeeper in Haiti. Photo: Robert Miller (CC)

As if Haiti didn’t have enough problems already… From ABC News:

Compelling new scientific evidence suggests United Nations peacekeepers have carried a virulent strain of cholera — a super bug — into the Western Hemisphere for the first time.

The vicious form of cholera has already killed 7,000 people in Haiti, where it surfaced in a remote village in October 2010. Leading researchers from Harvard Medical School and elsewhere told ABC News that, despite UN denials, there is now a mountain of evidence suggesting the strain originated in Nepal, and was carried to Haiti by Nepalese soldiers who came to Haiti to serve as UN peacekeepers after the earthquake that ravaged the country on Jan. 12, 2010 — two years ago today. Haiti had never seen a case of cholera until the arrival of the peacekeepers, who allegedly failed to maintain sanitary conditions at their base.

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Mystery Kidney Disease Epidemic in Central America

Central AmericaKate Sheehy reports for PRI’s The World:

In the western lowlands of Nicaragua, in a region of vast sugarcane fields, sits the tiny community of La Isla.The small houses are a patchwork of concrete and wood. Pieces of cloth serve as doors.

Maudiel Martinez emerges from his house to greet me. He’s pale, and his cheekbones protrude from his face. He hunches over like an old man — but he is only 19-years-old.

“The way this sickness is — you see me now, but in a month I could be gone. It can take you down all of a sudden,” he says. Maudiel’s kidneys are failing. They do not perform the essential function of filtering waste from his body. He’s being poisoned from the inside. When he got ill two years ago, he was already familiar with this disease and how it might end. “I thought about my father and grandfather,” he says.

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Fecal Matter Transplants Used to Cure Intestinal Infection

Clostridiumdifficile

C. difficile colonies on a blood agar plate.

James Gallagher reports in BBC News

Transplanting faecal matter from one person to another — the thought might turn your stomach, but it could be lifesaving.

Some doctors are using the procedure to repopulate the gut with healthy bacteria, which can become unbalanced in some diseases. Dr Alisdair MacConnachie, who thinks he is the only UK doctor to carry out the procedure for Clostridium difficle infection, describes it as a proven treatment. He says it should be used, but only as a treatment of last resort.

The logic is simple. C. difficile infection is caused by antibiotics wiping out swathes of bacteria in the gut. It gives the surviving C. difficile bacteria room to explode in numbers and produce masses of toxins which lead to diarrhoea and can be fatal.

The first-choice solution, more antibiotics, does not always work and some patients develop recurrent infection.

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Parkinson’s Disease Linked To Common Chemical

569px-Paralysis_agitans_(1907,_after_St._Leger)The petro-chemical industry likes to portray itself as the progenitor of our rapidly-advancing technological society, but it will come as little surprise to some that there is a price to be paid, principally to the health of our planet and our selves. Neil Bowdler reports on a new study showing a six-times greater likelihood of developing Parkinson’s disease after exposure to trichloroethylene (once used as a general anesthetic), for BBC News:

An international study has linked an industrial solvent to Parkinson’s disease.

Researchers found a six-fold increase in the risk of developing Parkinson’s in individuals exposed in the workplace to trichloroethylene (TCE).

Although many uses for TCE have been banned around the world, the chemical is still used as a degreasing agent.

The research was based on analysis of 99 pairs of twins selected from US data records.

Parkinson’s can result in limb tremors, slowed movement and speech impairment, but the exact cause of the disease is still unknown, and there is no cure.

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Mosquitoes That Are Genetically-Engineered to Self Destruct (To Prevent Disease) Are in the Air

MosquitoBijal P. Trivedi writes in Scientific American:

A new breed of genetically modified mosquitoes carries a gene that cripples its own offspring. They could crush native mosquito populations and block the spread of disease. And they are already in the air — though that’s been a secret.

Outside Tapachula, Chiapas, Mexico — 10 miles from Guatemala. To reach the cages, we follow the main highway out of town, driving past soy, cocoa, banana and lustrous dark-green mango plantations thriving in the rich volcanic soil. Past the tiny village of Rio Florido the road degenerates into an undulating dirt tract. We bump along on waves of baked mud until we reach a security checkpoint, guard at the ready. A sign posted on the barbed wire–enclosed compound pictures a mosquito flanked by a man and woman: Estos mosquitos genéticamente modificados requieren un manejo especial, it reads. We play by the rules.

Inside, cashew trees frame a cluster of gauzy mesh cages perched on a platform.

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UK Doctors Claim Gonorrhea Is ‘Drug Resistant’

PenicillinThe good ol’ days of penicillin …. Michelle Roberts reports for BBC News:

UK doctors are being told the antibiotic normally used to treat gonorrhoea is no longer effective because the sexually transmitted disease is now largely resistant to it. The Health Protection Agency says we may be heading to a point when the disease is incurable unless new treatments can be found.

For now, doctors must stop using the usual treatment cefixime and instead use two more powerful antibiotics. One is a pill and the other a jab.

The HPA say the change is necessary because of increasing resistance. Tests on samples taken from patients and grown in the laboratory showed reduced susceptibility to the usual antibiotic cefixime in nearly 20% of cases in 2010, compared with just 10% of cases in 2009.

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Addiction Is Not A Disease Of The Brain

OCDAlva Noe explains at NPR:

Addiction has been moralized, medicalized, politicized, and criminalized. And, of course, many of us are addicts, have been addicts or have been close to addicts. Addiction runs very hot as a theme.

Part of what makes addiction so compelling is that it forms a kind of conceptual/political crossroads for thinking about human nature. After all, to make sense of addiction we need to make sense of what it is to be an agent who acts, with values, in the face of consequences, under pressure, with compulsion, out of need and desire. One needs a whole philosophy to understand addiction.

Today I want to respond to readers who were outraged by my willingness even to question whether addiction is a disease of the brain.

Let us first ask: what makes something — a substance or an activity — addictive? Is there a property shared by all the things to which we can get addicted?

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Washington Health Sec.: Contagion Movie Is Very Real

Contagion[Note spoilers below and in the link.] Josh Kirns amps up fear of contagious diseases for Mynorthwest.com:

Talk about a horror movie. The global outbreak thriller “Contagion” topped the weekend box office and it prompted a lot of extra hand washing and increased hesitance to touch door knobs, hand rails, or just about anything else we all come in contact with. Of course it’s prompting many to ask if the fictional story of an unknown virus spreading around the world in a matter of days can come true.

“What was rolling around in my mind was when SARS happened,” Washington Secretary of Health Mary Selecky told Seattle’s Morning News on 97.3 KIRO FM. “And then of course, there was H1N1 (commonly known as Swine Flu,) it was an unknown novel virus just like in the movie.”

She said just like in the movie, we didn’t know what it was or how to treat it, and we didn’t have a vaccine.

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South Korean Scientists Clone Beagle That Glows Fluorescent Green

Could Tegon, the glowing dog, be the key to finding cures for many human diseases? Via Reutuers:

South Korean scientists said on Wednesday they have created a glowing dog using a cloning technique that could help find cures for human diseases such as Alzheimer’s and Parkinson’s, Yonhap news agency reported.

A research team from Seoul National University (SNU) said the genetically modified female beagle, named Tegon and born in 2009, has been found to glow fluorescent green under ultraviolet light if given a doxycycline antibiotic, the report said.

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