This is your brain on drugs, via Alternet:
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Sigmund Freud — Cocaine. To Freud, cocaine was more than a personal indulgence; it was a veritable wonder drug, and for many years he was a huge proponent of its use in a wide array of applications. Freud’s paper titled “Uber Coca” in 1884 was one of the first to propose drug substitution as a therapeutic treatment for addiction.
Francis Crick — LSD. Evidently, Crick – of the DNA-structure discovering Watson, Crick, and Franklin – at one point told a close friend that Cambridge University’s researchers often used LSD in small amounts as “a thinking tool” and he had actually “perceived the double-helix shape while on LSD.”
Thomas Edison — Cocaine Elixers. Thomas Edison was one of many people of the period known to regularly consume the cocaine-laced elixir “Vin Mariani,” a Bordeaux wine treated with coca leaves.
Steve Jobs — LSD.