It sounds totally sci-fi, but NASA appears to be serious about sending humans off into space to establish colonies without any hope of returning to Earth, per this report in the Daily Mail:
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NASA is planning an audacious mission to send a manned spacecraft on a one-way trip to permanently settle on other planets. The ambitious idea is known as the Hundred Years Starship and would send astronauts to colonise planets like Mars, knowing they could never come home.
NASA Ames Director Pete Worden revealed that one of NASA’s main research centres, Ames Research Centre, has received £1million funding to start work on the project. The research team has also received an additional $100,000 from Nasa.
‘You heard it here,” Worden said at ‘Long Conversation,’ an event in San Francisco. ‘We also hope to inveigle some billionaires to form a Hundred Year Starship fund.’ He added: ‘The human space program is now really aimed at settling other worlds.